The C++ language is a multi-purpose, object-oriented programming language with a wide range of applications. In accordance with the training objectives and curriculum characteristics of the biomedical engineering program of the School of Health Science and Engineering, University of Shanghai for Science and Technology, the reform of the C++ programming language course aims to organically integrate C++ programming with the design of intelligent medical instruments. The teaching content will focus on the C++ language’s application of intelligent medical device development, establishing project-based and modular teaching and practical content. Furthermore, a multi-dimensional collaborative mechanism and a multi-layered practical mechanism will be established within the teaching framework to ensure that the practical content of intelligent medical instrument design in C++ programming language course is effectively taught, with an emphasis on cultivating students’ practical skills and comprehensive abilities. Through this approach, the goal is to promote an in-depth understanding of C++ language’s applications in the field of biomedical engineering and to provide students with a solid foundation for future practice in the medical technology sector.