Objective To explore optimal solutions to maximize the remaining economic value, disposal efficiency, and storage site turnover in the process of medical equipment disposal, and investigate efficient pathways for medical equipment disposal in public hospitals. Methods Guided by relevant laws and regulations on medical equipment management, and based on the hospital’s internal control process, a comprehensive evaluation system is formed for the business income, depreciation cost, maintenance cost, and labor management cost of large medical equipment disposal. This system studies the remaining economic value evaluation model of large medical equipment as one of the basis for asset disposal. The medical equipment reporting and disposal process is optimized with the disposal principle of small and low value medical equipment of dispersed recycling, centralized temporary storage, and reporting by nodes, based on the annual approval timeline of the superior supervisory department. The storage area for medical equipment to be disposed of is divided based on asset attributes and disposal difficulty. Different areas are rotated according to different rhythms to ensure emergency storage space. Centralized disposal and transportation are implemented as much as possible to reduce transportation costs and meet environmental protection requirements. Effective technological means are explored to strengthen remote visual monitoring management. Results After implementing a wave like cleaning and storage rhythm and a closed-loop cleaning process, the disposal efficiency of small medical equipment has been significantly improved, long-term stockpiling is eliminated, the space turnover rate of storage warehouses has been effectively increased, and transportation and warehousing costs are reduced. Compared to those in 2019, the annual logistics cost decreases by about 33.3%, and the annual warehousing cost decreases by about 53.4% in 2023. Innovation This study explores an evaluation system for the remaining economic value of largescale medical equipment, optimize the disposal process of medical equipment with strong operability, and use effective technological means to strengthen remote visual monitoring management, providing a certain reference basis for the optimization of the disposal management system of medical equipment in public hospitals.